{"id":344634,"date":"2014-07-08T09:00:04","date_gmt":"2014-07-08T01:00:04","guid":{"rendered":"http:\/\/www.mariefranceasia.com\/uncategorized-hk\/cancer-du-in-test-for-detect-to-10-year-davance-344634.html"},"modified":"2014-07-08T09:00:04","modified_gmt":"2014-07-08T01:00:04","slug":"cancer-du-in-test-for-detect-to-10-year-davance","status":"publish","type":"post","link":"https:\/\/www.mariefranceasia.com\/hk\/health-hk\/medical-news-hk\/cancer-du-in-test-for-detect-to-10-year-davance-344634.html","title":{"rendered":"Breast cancer: A test to detect the risk of disease - 10 years ahead"},"content":{"rendered":"<p class=\"p\" style=\"color: #393736\"><a href=\"http:\/\/www.mariefranceasia.com\/wp-content\/uploads\/sites\/7\/2014\/06\/breast-cancer.jpg\"><span style=\"display: block;\" class=\"wrap-img\" id=\"wrap-img-30916\"><img loading=\"lazy\" decoding=\"async\" itemprop=\"thumbnailUrl\" class=\"aligncenter wp-image-30916 img-responsive  size-medium\" src=\"http:\/\/www.mariefranceasia.com\/wp-content\/uploads\/sites\/7\/2014\/06\/breast-cancer-625x341.jpg\" alt=\"breast cancer\" width=\"625\" height=\"341\" \/><\/span><\/a><\/p> <p class=\"p\" style=\"color: #393736\">Regarding\u00a0the prevention of breast cancer, we hear a lot about the detection of mutations in the BRCA1 gene. When it is proved, women have 85% risk of developing the disease. In these cases, mastectomy may be recommended for prevention. But these \"anomalies\" are in the minority and concern only\u00a010% of breast cancers. In 90% of the cases, there are no signs or markers\u00a0to predict the risk. Today, we know that it is not just the genetics\u00a0-\u00a0environmental factors also have a great influence on the way\u00a0our genes function. This is called epigenetics. Simply put, what we eat, whether we exercise\u00a0or pollution can for example \"turn on\" or \"turn off\" certain genes protecting against certain diseases or, on the contrary, it can expose us to others.<\/p> <p>In a study published on June 27 in the Genome Medicine journal, British researchers analysed blood samples taken from a\u00a0few hundred women over a period of\u00a0several years. Their goal: to find those in which DNA methylation was observed - as it is one of the best known epigenetic markers - and see if there was a link with the future development of breast cancer. According to Professor Martin Widschwendter, who led the study: \"When this DNA methylation was\u00a0found in women who have a mutation in the BRCA1 gene, the risk of breast cancer was\u00a0highest and it had the lowest survival rate . We were surprised to discover that the same modification of DNA in women with no risk of hereditary breast cancer was also linked to developing\u00a0the disease a few years later.\"<\/p> <p><strong>The explanation:<\/strong> This methylation could \"turn off\" some genes, which as a\u00a0result would affect the proper functioning of our immune system and its role in the prevention of breast cancer. Further research is needed to determine whether this epigenetic marker\u00a0is an indicator of risk or if it is more of a reaction related to the process of development of the disease.<\/p> <p>For Professor Widschwendter: \"These data are encouraging because they show the potential of a blood-based test to detect epigenetic risk of breast cancer among women with no genetic predisposition\".<\/p> <p>The question is what do we do with the results if the tests are positive, especially as\u00a0so far scientists have little data on how to modify genes' expression. Is it possible to reverse the process through changes in behavior? Or these new detection methods will just\u00a0be another thing to worry and be wary about?<\/p>  <h5> <span><strong>Read more on our breast cancer report:<\/strong><\/span> <\/h5> <p><a href=\"http:\/\/www.mariefranceasia.com\/health\/healthy-practices\/seins-les-vertus-de-lautopalpation-28613.html#post-28613\">How to self-examine your breasts<\/a><\/p> <p><a href=\"http:\/\/www.mariefranceasia.com\/health\/medical-news\/cancer-du-sein-moins-de-faux-diagnostics-avec-la-mammographie-3d-29473.html#post-29473\">The most reliable 3D mammography<\/a><\/p> <p><em>Maureen\u00a0DIAMENT<\/em><\/p>  <p class=\"p\" style=\"color: #393736\"> ","protected":false},"excerpt":{"rendered":"<p>A team of British scientists has identified a change in the cells that would indicate many years in advance the women who have a high risk of being affected with the disease, even in the absence of hereditary factors.<\/p>\n","protected":false},"author":54,"featured_media":30916,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_metadesc":"A team of British scientists has identified a change in the cells that would indicate many years in advance the women who have a high risk of being affected, even in the absence of hereditary factors.","_is_translated":false,"_source_post_url":"","is_displayed_in_hp":false,"displayed_in_hp_after_update":false,"is_thumb_featured":false,"template_without_diapo":"","enable_bloc_resume":false,"bloc_resume_post":[],"ctc_post":false,"footnotes":""},"categories":[16904],"tags":[],"class_list":["post-344634","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-news-hk"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - 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